Mamutan Research

Mamutan Research is an independent, self-directed research effort — a standing home for enquiry that follows curiosity rather than a funding cycle, and shares what it finds openly.

It is not tied to any single subject. The aim is durable: to host successive lines of enquiry as they arise, to set ideas down carefully and citably, and to leave a clear record that others can build on, test, or refute. Where the work is speculative, it is offered honestly as conjecture — reasoning under uncertainty, put forward for others to examine.

Founded and directed by Arthur D. Hall, PhD — Cambridge, UK.

The current programme concerns lithium orotate and the brain's relationship with trace lithium. In 2025 a team at Harvard reported that the amyloid plaques of Alzheimer's disease can sequester the brain's own lithium, and that the orotate form of lithium appears to evade this trap. That finding raises two deeper questions the published work does not settle: why would a trace element matter to the neuron at all, and how might the orotate form reach the brain? Mamutan's work explores both, as a set of testable conjectures.

These conjectures are explored in the book Hope for Alzheimer's and Dementia: Lithium Orotate, the Story of a Mineral, published by Figurine Press, and set out in the citable preprints below.

Findings are shared first as open preprints, so that the work carries a clear, citable date and is freely available to anyone who wishes to read or test the findings.

Mamutan Research is looking for collaborators. The conjectures set out here are testable, i.e. refutable by experiment — and the most useful thing anyone could do is to test them rigorously, including to destruction.

Independent work anywhere can only reach so far on its own. Judging these ideas properly calls for laboratories, clinical and analytical expertise, and the scrutiny of established researchers — the rigour that academic and scientific institutions exist to uphold. Mamutan Research would welcome the chance to work with partners in academia, industry, and the charity and NGO sectors — either in Cambridge, where this work is based, or anywhere around the world.

The aim is modest and specific: to have the science judged on its merits, under proper standards, by people equipped to judge it. A single experiment, a critical reading, an attempt at replication, or simply a conversation — all are welcome, and all are approached in the same spirit the work itself is offered: sceptically, and in good faith.

If any of this resonates, please write — see Correspondence below.

Mamutan Research welcomes correspondence from researchers, readers, and anyone working on related questions.

contact@mamutan.org